However, it is unknown whether mPGES-1/PGE2 signalling modulates EGFR expression levels.We measured EGFR expression in DU145 mPGES-1SC and mPGES-1KD cells, in tumours from mice inoculated with the respective cell lines and in DU145 and PC-3 treated with MF63. The gene discussed is EGFR; the disease is neoplasm.