CD44 and posterior cortical atrophy: This was indicated by the large increase in the CD44+/CD24− ratio, the decrease in α6-integrin and the increase in β1 integrin, as well as transcription factors Nanog and Oct4 in mPGES-1SC (Fig. 3A, B and C), all pluripotency maintaining factors overexpressed in PCa stem cells (Klarmann et al. 2009, Rentala et al. 2010, Marthick & Dickinson 2012, Nanta et al. 2013, Hoogland et al. 2014).Similar results were obtained for the PC-3 cell line.