In line with the role of PGE2 in cancer cell growth and E-cadherin expression (Castellone et al. 2005, Lu et al. 2012), we found massive translocation of β-catenin into the nucleus of DU145 mPGES-1SC cells, while it remained localized in the cytoplasm of mPGES-1KD cells (Fig. 2E and F). The gene discussed is CDH1; the disease is cancer.