CASP3 and breast carcinoma: In our study, the induction of apoptosis by new platinum complex with anti-MUC1 in human MDA-MB-231 breast cancer cells was confirmed by several biochemical markers, such as phosphatidylserine externalization, loss of MMP ΔΨm, DNA degradation, Bax, and caspase-3, -8, -9 levels.