On examining IL10 production by CD19+ CD24hi CD38hi B cells on stimulation by LPS no significant differences were observed between our groups, F(2, 41) = 2.03, p = .14, η2 = .43 (Fig. 4d), although a trend towards a decline in IL10 production by Bregs was observed in hip fracture patients with depressive symptoms. Here, CD19 is linked to hip fracture.