There was a significant association between GDS scores and the frequency of IL10 producing CD19+CD24hiCD38hi B cells post stimulation in hip fracture patients, β = −0.34, p = .03, ΔR2 = 0.34, such that hip fracture patients with greater depressive symptoms (GDS score) had a lower frequency of CD19+CD24hiCD38hi B cells (Fig. 4c). Here, IL10 is linked to hip fracture.