Among the studied genes, RASSF1A showed the highest methylation level: 52 % in total NSCLC group, 50 % in SCC, and 66 % in AC; NPRL2/G21 – the lowest: 5 % in total NSCLC group, 3 % in SCC, and 10 % in AC. Here, RASSF1 is linked to non-small cell lung carcinoma.