NPPB and atherosclerosis: Among the other markers of atherosclerosis, BNP, which is secreted mainly by the ventricular myocardium53, 54, 55, has been found to decrease significantly by the GLP-1-based therapies but MCP-1, which is secreted by the peripheral blood mononuclear cells56, has been found un-affected by the GLP-1-based therapies, in the present study.