In addition, we also show that for CML patients being monitored for MRD, applying this test is a simple and effective approach for the rapid screening of responses during the initial 3 or 6 months of TKI therapy to detect an early molecular response (EMR, defined as BCR-ABL1IS<10%) [37–38]. Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.