MED30 induced the expressions of EMT-related genes (N-cadherin; CDH2, P-cadherin; CDH3, twist related protein 1 and 2; TWIST1/2, vimentin; VIM), but inhibited the expression of E-cadherin (CDH1) a known tumor suppressor (Fig 6A and 6B). This evidence concerns the gene CDH1 and neoplasm.