As shown in Fig 5B and 5C, inverse relationships were existed between the expression of Let-7a and TNFAIP3(r = —0.42, p = 0.0029) or Let-7e and TNFAIP3(r = —0.33, p = 0.025) in LN patients. Here, TNFAIP3 is linked to lobular neoplasia.