KRT18 and primary biliary cholangitis: Caspase-cleaved CK-18 fragments (M30 assay) and total CK-18 (M65 assays) have already been correlated with fibrosis stage in several chronic liver diseases.[9–11, 14, 15] Similarly, we found a significant correlation between M30, M65, and M65ED levels and histological fibrosis PBC.