High expression levels of Rabs were observed in invasive OSCC tissues (overall expression values of Rab5, Rab7 and Rab11 were 80.8%, 90.4%, and 55.8%, respectively), while in morphologically normal oral epithelium surrounding cancer lesions expression of these Rabs was very low to undetectable (Figure 2A). Here, RAB5A is linked to cancer.