PTPRC and neoplasm: Also as for those CICs with CD45+ leukocytes internalized, it will be interesting to further characterize what kind of leukocytes were internalized since a range of them had been reported before, including NK cells, T and B cells, and neutrophils etc. Due to limited samples for each tumor type, we didn't perform an association analysis between CICs, frequency or subtype, and clinical features, however, valuable information would be expected in future if large number of tissues were examined.