The list contained several genes responsible for CRC development or metastasis, including BMI1 [23], HOXB9 [24], PLXNB1 [25], POLD1 [26], TGIF1 [27], SOX9 [28], as well as TP53 (Supplementary Table S7). Here, TGIF1 is linked to colorectal carcinoma.