High abundance of HSPB1 was detected in grade IV astrocytoma, particularly in GBM-SS (5 months, Fig. 3d(e)) with unequivocal contrast to the weak labeling of a GBM-LS case (27 months, Fig. 3d(f)). The gene discussed is HSPB1; the disease is astrocytoma (excluding glioblastoma).