LMO2 expression has also been reported in some B cell acute leukaemias (B-ALL) with differing prognostic correlations, where there is good prognostic association in some [115,118], but in others, such as B-ALL expressing the E2A–HLF fusion from t(17;19) (q22;p13), it is a poor prognostic feature [113,114]. Here, LMO2 is linked to precursor B-cell acute lymphoblastic leukemia.