In subgroups with oesophageal varices (n = 87) and renal impairment (n = 22), IL-6 was the only biomarker which concentrations significantly differed in comparison to ALD individuals without aforementioned complications (median; 95% CI: 24.63; 18.65–28.30 versus 15.92; 9.79–24.82; p = 0.04; and 31.14; 26.44–108.34 versus 20.07; 15.68–24.62; p = 0.003, respectively). The gene discussed is IL6; the disease is esophageal varices.