Neither AT1b nor AT2 receptor–deficient mice exhibit anemia [AT1a(+/-) AT1b(-/-), 46.23 ± 0.68% (n = 6); not significant vs. WT; AT2(-/-), 47.39 ± 2.89% (n = 18); p = 0.0028 (ANOVA followed by Tukey’s HSD post hoc comparisons) vs. WT] (Fig 4). The gene discussed is AGTR2; the disease is anemia (phenotype).