In D-LN from mice infected with NP-S-EGFP, we visualized OT-I TCD8+ interacting with EGFP+CD169+ macrophages (Fig 3F), EGFP+CD11c+ DC (Fig 3H), EGFP+CD103+ DC (Fig 3J) and, surprisingly, EGFP+B220+ B cells (Fig 3D) within 24 h of infection. This evidence concerns the gene SIGLEC1 and infection.