Anti-CMV IgG (analyzed before IVIG administration) and IgM were positive in blood sample, as was CMV nucleic acid in the urine (4–6 × 104 copies/mL, Table 1), suggesting the presence of or recent recovery from a CMV infection, which represents a potential trigger of immune-mediated platelet destruction. The gene discussed is CD40LG; the disease is cytomegalovirus infection.