Based on the analysis of the spatial structure of p42.3 and Bayesian regulatory network, expressions of S100A11 (the protein with the largest positive maximum weighted value) and S100A2 (the protein with the shortest negative acting path) in gastric carcinoma cell lines were examined, respectively, for preliminary valediction of the correlation of p42.3 and S100A11. The gene discussed is S100A2; the disease is gastric carcinoma.