Following the above findings with different design, prospective study, conducted at the Endocrinology, Diabetes and Metabolic Diseases Clinic at the University Center of Sarajevo, 50 patients diagnosed with PCOS in accordance with the Rotterdam criteria – ESHRE [5] were divided into two groups according to their BMI and had the following parameters evaluated: anthropometric indices (WC, height and weight), BMI, TG, resistance to insulin and the LAP index. Here, INS is linked to metabolic disease.