Consistent with their tumorigenic induction and promotion of anchorage independent growth of NIH3T3 and NIH3T3-KRAS12V cells, there was a reciprocal increase and decrease in secreted CXCL1 and IL8 levels by SW620 and CRC-MF cells as a result of serum deprivation. This evidence concerns the gene CXCL8 and colorectal carcinoma.