We demonstrated that p-ERK1/2 and p-AKT activation was statistically different between control cancer-free and NSCLC tissues; in fact, cancer specimens have a significantly higher expression of p-ERK1/2 and p-AKT compared to the control (p < 0.05) (Fig. 1a, and b, respectively). This evidence concerns the gene AKT1 and non-small cell lung carcinoma.