VPS13B and autism: Re-analyzing exome sequencing data of 488 ASD cases and 372 controls from the ARRA Autism Sequencing Collaboration (AASC) project, Ionita-Laza I et al. found two loss-of-function variants (one nonsense: p.Ser3383* and one splice site: c:2650 + 2 T > G), and a rare, homozygous probably-damaging variant (p.Arg3198Trp) in VPS13B that could contribute to autism risk [33].