Importantly, we noted that the most significantly enriched pathway was Pathways in cancer, which refers to some classical pathways such as Wnt signaling pathway, PI3K-Akt signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, ErbB signaling pathway and some others together to regulate tumor growth and metastasis[25]. The gene discussed is AKT1; the disease is neoplasm.