EEF1A1 and Hepatic steatosis: Our studies revealed that: 1) during exposure of hepatocytes to high palmitate, eEF1A-1 protein is modestly induced and partially redistributes from its predominant subcellular location at the ER to polymerized actin at the cell periphery, preceding cell death, 2) chemical inhibition of eEF1A-1 peptide elongation activity decreases palmitate-induced death in hepatocytes in association with sustained inhibition of protein synthesis, and 3) liver eEF1A-1 protein is induced in obese mice with severe hepatic steatosis.