In an effort to replicate our findings from the DNHS, we tested for association between variants in GRM1, GRM5, HOMER1, HOMER2, EEF2K, MTOR, EIF4E, EEF2, CAMK2A, ARC, GRIA1, GRIA4 and alcohol use behavior (AUDIT) in the GTP. The gene discussed is GRIA4; the disease is alcohol dependence.