SERPINE1 and breast carcinoma: High levels of PAI-1 in breast cancer thus, is linked to the poor prognosis of disease progression (Carter and Church 2009, 2012; Andreasen et al. 2000; Bianchi et al. 1995; Gomes-Giacoia et al. 2013; Gutierrez et al. 2000; Sumiyoshi et al. 1991; Offersen et al. 2003; Jankun et al. 1993; Foekens et al. 2000).