MKI67 and breast cancer: Nowadays, Ki67 scoring is used as a prognostic factor for early breast cancer and even as a predictor of its treatment efficacy (Pathmanathan and Balleine 2013; Urruticoechea et al. 2005; Bullwinkel et al. 2006; Luporsi et al. 2012; Inwald et al. 2013; Nishimura et al. 2010).