F2 and coronary artery disorder: In their paper titled “The Difference Quantity of Urinary Peptides between Two Groups of Type 2 Diabetic Patients with or without Coronary Artery Disease,” G. Fu et al. examined T2DM patients and noted significant differences in the expression of peptides (fragments of isoform 1 of fibrinogen alpha chain precursor, prothrombin precursor, and inter-alpha-trypsin inhibitor heavy chain H4) between those with CAD and those without CAD, suggesting that we need to consider how such differences may be practically utilised in the search for CAD biomarkers.