GLUT-1 is widely lowly expressed in normal tissues as the main carrier responsible for the transmembrane transport of glucose, but it is highly expressed in endometrial cancer, cervical squamous cell carcinoma, ovarian cancer and colon cancer.19 GLUT-1 is also a good marker for differentiating benign endometrium from atypical hyperplastic one, with the former having no or weak expression and the latter having different degrees of diffusive expression. The gene discussed is SLC2A1; the disease is cervical squamous cell carcinoma.