The mRNA analysis by qPCR in the explanted melanomas of a panel of different inflammatory factors showed a significant accumulation at B16-W6_pSIL10 tumour site of interleukin- (IL-) 1β, IL-6, IL-10, granulocyte-macrophage colony-stimulating factor (GM-CSF), transforming growth factor- (TGF-) β1, and tumour necrosis factor- (TNF-) α (Figure 1(a)). This evidence concerns the gene IL6 and neoplasm.