Expression levels of SC gIDs such as IL6ST and DUSP6, which were found in 7 and 8 BC rGSSs respectively (Additional files 4 and 5), were found to be able to stratify both Stockholm and Uppsala BC patient cohorts into two survival significant subgroups via the data-driven grouping method (Figures 6C-D). The gene discussed is DUSP6; the disease is breast cancer.