WNK2 and esophageal cancer: Some scholars from Xinjiang [4] have found that the changes of extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) signaling pathway activation level may get involved in the occurrence of Kazakh patients of early esophageal cancer by RT-PCR; as a result, nowadays, it is essential to find predict tumor markers of the prognosis of patients with esophageal cancer in Xinjiang.