In the network, hsa-let-7b-5p had the highest connectivity, 15 amplified genes and 2 deleted genes were under its regulation, including amplified AURKA (mentioned above), SNRPE in the spliceosome pathway, BIRC5 involved in the cancer pathways, and deleted USP10 which is involved in the MAPK signaling pathway. This evidence concerns the gene AURKA and cancer.