COMT and temporomandibular joint disorder: A genetic contribution is reported in a few prospective studies on whiplash injuries, and similar painful conditions [38,39], where persons with high pain sensitive haplotypes of COMT-alleles carry a raised risk for long-term disability after whiplash injuries, but also risk for development of other so-called idiopathic pain disorders as TMD/TMJ (Temporomandibular disorders/Temporomandibular joint disorders) and fibromyalgia.