PLA2G7 and familial isolated congenital asplenia: Similarly, in simple adjusted logistic regression analysis, Lp-PLA2 mass were significantly associated with isolated moderate to severe ICAS (OR: 3.63; 95% CI: 1.16–11.3), concurrent moderate to severe extraintracranial stenosis (OR: 15.39; 95% CI: 2.03–116.55), and complex moderate to severe ICAS (OR: 3.57; 95% CI: 1.37–9.33).