For instance, Yamashita and colleagues [72] have found that AFP could be used with EpCAM to define cancer cells with stem cells features and demonstrated that EpCAM+ and CD90+ cells resided distinctively; furthermore, gene expression's analysis of sorted cells suggested that EpCAM+ cells had features typical of epithelial cells, whereas CD90+ cells had those typical of vascular endothelial cells. The gene discussed is EPCAM; the disease is cancer.