AICDA and breast carcinoma: Recent work presents evidence that this inflammation-induced AID expression is required for epithelial to mesenchymal transition in ZR75.1 breast cancer cells and non-transformed mammary epithelial cells, since AID deficiency in these cells suppresses expression of key transcriptional regulators for epithelial to mesenchymal transition and is associated with increased cytosine methylation in promoters of these genes [123].