RNPC3 and systemic lupus erythematosus: Intraperitoneal injection of pristane in non-autoimmune prone mice, such as B6 or BALB/c, causes a lupus-like syndrome with high levels of IgG anti-dsDNA, anti-Sm/RNP, anti-Su, anti-ribosomal P, and other lupus-related autoantibodies starting ~3 months after treatment (54).