AIDS is a lethal infectious disease of the immune system caused by the human immunodeficiency virus (HIV), which can be viewed as a paradigm for P. vivax-induced-malaria since like its protozoal counterpart, it requires an interaction between an HIV protein, the viral glycoprotein gp120, and either one of the human chemokine receptors CCR5 or CXCR4. This evidence concerns the gene CCR5 and AIDS.