Transplant scientists in China have also established the Shanghai Fudan criteria (similar to the UCSF criteria, extending the diameter to 9.0 cm for a solitary nodule, 5.0 cm for the largest nodule, and 9.0 cm as the total diameter when multiple nodules are present) and Hangzhou criteria (a total tumour diameter 8 cm or less or a total tumour diameter of greater than 8 cm with an Edmondson grade I or II and pre-operative alpha-fetoprotein level of 400 ng/mL or less simultaneously). The gene discussed is AFP; the disease is neoplasm.