Lethally irradiated C57BL/6 recipient mice were transplanted with wild-type (WT) bone marrow, either transduced with MiG-empty retrovirus (GFP-marked) or subjected to combined infection with ASXL1(1–479)-IRES-GFP+BAP1-IRES-Thy1.1 retroviruses (Fig. 6b and Supplementary Fig. 6a). Here, BAP1 is linked to infection.