In addition, multivariate analysis showed that vimentin expression (HR, 2.008; 95% CI, 1.191–3.384), tumor status (HR, 1.830; 95% CI, 1.049–3.194) and lymph node metastasis (HR, 5.77; 95% CI, 2.221–15.028) were independent predictors of mortality in ESCC (Table V). Here, VIM is linked to neoplasm.