Although this dataset does not contain survival data, the correlations between SPR expression and three important clinical NB parameters are highly significant (Fig. 2, a-c): age at diagnosis (P = 1.9 · 10−23, MYCN tumor amplification (P = 7.9 · 10−15, and INSS stage (various P values < 0.05). The gene discussed is MYCN; the disease is neoplasm.