Among the sequestered proteins are the alternative splicing regulator proteins of the Muscleblind-like family (MBNL1-MBNL3), which have been linked to crucial DM1 features (Du et al., 2010; Fardaei et al., 2001; Jiang et al., 2004). The gene discussed is MBNL1; the disease is myotonic dystrophy type 1.