MYO1E and kidney disorder: Mutations in the MYO1E gene in humans are associated with focal segmental glomerulosclerosis (FSGS) (Al-Hamed et al., 2013; Mele et al., 2011; Sanna-Cherchi et al., 2011), a kidney disease arising from the disruption of the protein filtration barrier in the kidney, which leads to proteinuria (protein excretion in the urine).