Since our examination of the DNA methylation status of BSND and ATP6V1G3 in RCC was an in silico analysis, future alternative experimental analyses, such as methylation-specific polymerase chain reaction, towards CpG sites near the TSS of BSND and ATP6V1G3 would further endorse our suggestion on the relationship between DNA methylation and the expressions of these genes. This evidence concerns the gene ATP6V1G3 and renal cell carcinoma.