Furthermore, TGFβ2 is a known downstream effector of β1 integrin and upregulation of TGFB2 expression has been reported to be associated with migration and cancer dormancy [34, 35], we examined and found that TGFB2 expression was consistently downregulated in G when compared to NG cells in all three LuCaP PDX lines by real-time qPCR (Fig 3E). The gene discussed is TGFB2; the disease is cancer.