Of the 95 SLE patients, 33 patients were positive for APL, 51 for antihistone antibody, 46 for anti-P0, 51 for anti-SSA/Ro52 kD, 61 for anti-SSA/Ro60 kD, 34 for anti-SSB/La, 38 for antinucleosome, 30 for anti-U1RNP, 45 for anti-SM, and 63 for anti-dsDNA. This evidence concerns the gene SSB and systemic lupus erythematosus.