Higher anti-CCP2 titers were found in patients with RA-ILD compared to RA only (77.9 versus 30.2 U/mL, P < 0.001); the frequency of positive rheumatoid factor (RF) was also higher in RA-ILD (97.4% versus 35.7%, P < 0.001), and levels of ESR were higher in ILD (32 versus 19.5, P < 0.001). The gene discussed is AGBL2; the disease is interstitial lung disease.