IL10 and anemia: In contrast, M2-type MYPS cells (alternatively activated myeloid cells) in trypanotolerant animals (exhibiting reduced anemia/ACD) induced via IL-10 or IL4/IL13 promote induction of anti-inflammatory cytokines like IL-10 (crucial for dampening the pathogenic effects of proinflammatory cytokines) and export of iron [139–141].